Blar i UiS Brage på forfatter "Evangelista, Tereza Cristina Santos"
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Development of tacrine clusters as positively cooperative systems for the inhibition of acetylcholinesterase
Evangelista, Tereza Cristina Santos; Lopez, Oscar; Ferreira, Sabrina Baptista; Fernandez-Bolanos, Jose G.; Sydnes, Magne Olav; Lindback, Emil (Peer reviewed; Journal article, 2021-07)The synthesis of four tetra-tacrine clusters where the tacrine binding units are attached to a central scaffold via linkers of variable lengths is described. The multivalent inhibition potencies for the tacrine clusters ... -
A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE)
Evangelista, Tereza Cristina Santos; Lopez, Oscar; Puerta, Adrian; Fernandes, Miguel X.; Ferreira, Sabrina Baptista; Padron, Jose M.; Fernandez-Bolanos, Jose G.; Sydnes, Magne Olav; Lindback, Emil (Peer reviewed; Journal article, 2022)The synthesis of four heterodimers in which the copper(I)-catalysed azide-alkyne cycloaddition was employed to connect a 1-deoxynojirimycin moiety with a benzotriazole scaffold is reported. The heterodimers were investigated ...